CryoNews

The crucial role of cryogenics in cell and gene therapy

In the rapidly evolving field of cell and gene therapy, careful preservation of starting materials is a cornerstone of success. Cryogenics plays a pivotal role here, reshaping the landscape by controlling variability, ensuring viability, and optimizing the efficacy of immune cell therapies. Let's discover the essential role of cryopreservation and its groundbreaking techniques that are paving the way for a new era of excellence in cell and gene therapy.

What is cryopreservation?

Cryopreservation is an important technology in regenerative medicine that enables stable and safe long-term storage of primary tissue isolates and cell preparations and includes cryoprotection, cooling, freezing, storage, transport, thawing, and retrieval.

❗️ The need for cryopreserved cellular starting materials:

While freshly isolated starting materials are the gold standard, their rapid deterioration requires a groundbreaking solution. Cryopreservation is proving to be a cornerstone of stability, ensuring the viability and quality of starting materials until their use. Storage at room temperature and refrigeration temperatures has limitations, underscoring the importance of cryopreservation for the successful implementation of cell-based therapies.

Important advantages of cryopreserved starting materials:

1️⃣ Reducing procurement concerns:

Cryopreservation ensures on-demand availability, thus reducing concerns about donor procurement.

2️⃣ Risk reduction and simplified logistics:

By ensuring product quality, reducing shipping risks, and protecting against unforeseen shipping delays, cryopreservation fits seamlessly with the stringent logistical requirements of cell and gene therapy.

3️⃣ Planification stratégique and répartition des fourniture:

Cryopreservation allows for careful planning and management of the materials to be processed, thereby reducing costs and minimizing material waste.

4️⃣ Maintaining cell quality and viability:

A feature of cryopreservation is its ability to extend shelf life and maintain the vitality and functionality of cells until their required use.

5️⃣ Ensuring consistency of downstream processing:

Cryopreserved materials offer a flexible approach for downstream event planning and ensure continuous access to reliable cellular starting materials.

⛑️ Ensuring cell quality through cryopreservation:

Ensuring the greatest possible success in cryopreservation requires optimized processes and expertise. With more than three decades of meticulous development of cryopreservation protocols, Consarctic stands for a tireless commitment to ensuring maximum viability and functionality.